SV40 viral vectors for targeted integration into cells

Details SV40 viral vectors for targeted integration into cells SV40 viral vectors for targeted integration into cells

1997-12-31

1999-01-26

Ketter, James

Chemistry: molecular biology and microbiology

Vector, per se

C12N 1586

Patent

active

058637940

ABSTRACT:
A vector capable of integrating into a selected site of a cell's genome is provided which contains a replication-deficient SV40 virus and a nucleic acid sequence flanked with integration promotion sequences.

REFERENCES:
Ochman et al., "Genetic Applications of an Inverse Polymerase Chain Reaction", Genetics1988 120:621-623.
Takagi et al., "A Rapid and Efficient Protocol of the Inverted PCR Using Two Primer Pairs", Biotechniques1992 13:176-178.
Strayer et al., Gene Therapy,vol. 3, 1996, pp. 581-587 (Abstract only).

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