Suturable adhesion-preventing membrane

Fabric (woven – knitted – or nonwoven textile or cloth – etc.) – Nonwoven fabric – Including a foamed layer or component

Reexamination Certificate

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Details

C442S373000, C442S374000, C442S123000, C606S228000, C606S229000, C606S230000, C606S231000, C424S422000, C424S423000

Reexamination Certificate

active

06977231

ABSTRACT:
A suturable adhesion-preventing membrane has high suture strength, good biocompatibility, decomposition and absorption in a living body, sufficient adhesion-preventing effect, and desirable guided tissue regeneration. The membrane is composed of at least one non-woven fabric layer made of collagen fibers, or a laminated membranous substance consisting of at least one non-woven fabric layer made of collagen fibers and at least one sponge layer made of collagen, and a coating layer of gelatin or hyaluronic acid on the surface or surfaces of the above membrane. Preferably, the membrane comprises one to six compressed cross-linked collagen non-woven fabric layers wherein a layer has a fibers having a fiber diameter of 0.05 mm to 1.0 mm, a bulk density of 5.0×10−4to 5 g/cm3and a thickness of 0.1 mm to 50 mm, and a coating layer containing gelatin or hyaluronic acid and having a thickness of 0.05 mm to 20 mm, wherein the coating layer covers one or both sides or a part or whole of the surface of the membrane.

REFERENCES:
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Database WPI, Section Ch, Week 199828, Derwent Publications Ltd., London, GB, AN 1998-315641, XP002136590 & JP 10 113384 A

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