Sustained release tablet containing indapamide

Details Sustained release tablet containing indapamide Sustained release tablet containing indapamide

2002-07-24

2009-06-30

Hartley, Michael G (Department: 1618)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

C424S464000, C424S468000

Reexamination Certificate

active

07553499

ABSTRACT:
The present invention relates to a sustained release tablet containing indapamide and the process of manufacturing sustained release tablet containing indapamide. The tablet contains indapamide in the amount of 1.5 to 2.5% of the total mass of the tablet, lactose monohydrate in the amount of 30 to 80% of the total mass of the tablet, copovidone in the amount of 2 to 10% of the total mass of the tablet, hypromellose in the amount of 20 to 65% of the total mass of the tablet and lubricants in the amount of 0.1 to 5% of the total mass of the tablet. The process of manufacturing the sustained release tablet consists in mixing of indapamide with lactose monohydrate and copovidone and then, the mixture is moistened by purified water and the granulation process of it is performed. Next the granulate is dried, cooled, mixed with hypromellose and lubricants and compressed in tableting machine.

REFERENCES:
patent: 5334392 (1994-08-01), Cuine et al.
patent: 6077534 (2000-06-01), Tobin et al.
patent: 6294200 (2001-09-01), Conte et al.
patent: 3602304 (1986-08-01), None
patent: 0519820 (1992-12-01), None
patent: 1057479 (2000-12-01), None
patent: 2123293 (1984-02-01), None
patent: 2173399 (1986-10-01), None
Damien et al, Galenic Development and Pharmacokinetic Profile of indapamide Sustained Release 1.5mg, 1999, Clin Pharmaco, 37, Suppl 1 (XP009004369).
G. Damien et al., Clinical Pharmacokinetics, vol. 37, Suppl. 1, pp. 12-19, 1999.

Affiliated with

Also associated with

Rating

Sustained release tablet containing indapamide does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Sustained release tablet containing indapamide, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sustained release tablet containing indapamide will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4142921