Sustained-release tablet based on isosorbide 5-mononitrate and p

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills

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424468, 424464, 424470, A61K 920

Patent

active

053343930

ABSTRACT:
The present invention relates to a sustained-release tablet, characterized in that it comprises as active principle isosorbide 5-mononitrate (5-ISMN) in the form of a powder having a particle size of 80 .mu.m to 500 .mu.m, in homogeneous dispersion in a hydrophilic matrix based on at least one swelling component and at least one diluent component.

REFERENCES:
Budavari et al. (1989), The Merck Index, p. 5120.
Gennaro (1985) Remington's Pharmaceutical Sciences, Mack Pub., p. 853.

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