Sustained release preparations

Details Sustained release preparations Sustained release preparations

1995-02-14

1997-01-14

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424486, 424458, 424459, 424461, 424462, 424470, 424490, 424494, 424495, 424497, 424501, 514785, 514951, 514963, 514965, A61K 916, A61K 926, A61K 950, A61K 4734

Patent

active

055936903

ABSTRACT:
There is provided a matrix preparation produced by dispersing a pharmaceutically active ingredient into a matrix which is solid at ambient temperature and comprised of a fatty acid ester of a polyglycerol. The preparation has stable release-controlling ability, can be processed to fine granules, granules, capsules, tablets etc., and contributes to reduce the administration times of the active ingredient and side effects of the ingredient.

REFERENCES:
patent: 3857933 (1974-12-01), Ross et al.
patent: 4751241 (1988-06-01), Motoyama et al.
patent: 4777050 (1988-10-01), Vadino et al.
patent: 4806337 (1989-02-01), Swipes et al.
patent: 4844907 (1989-07-01), Elger et al.
patent: 4857336 (1989-08-01), Khawna et al.
M. R. Baichwal et al., "Sustained Release Capsules", The Indian Journal of Pharmacy, vol. 35, No. 5, Sep.-Oct. 1973, pp. 146-150.
Carstensen et al., "Physical and Chemical Properties of Calcium Phospates for Solid State Pharmaceutical Formulations", Drug Development & Industrial Pharmacy, 16(7), pp. 1121-1133, 1990.
Patent Abstract of Japan, vol. 8, No. 145, Jul. 6, 1984.

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