Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules
Patent
1991-12-13
1995-03-21
Webman, Edward J.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Capsules
424486, 424458, 424459, 424461, 424462, 424470, 424490, 424494, 424495, 424497, 424501, 514785, 514951, 514963, 514965, A61K 916, A61K 926, A61K 950, A61K 4734
Patent
active
053993578
ABSTRACT:
There is provided a matrix preparation produced by dispersing a pharmaceutically active ingredient into a matrix which is solid at ambient temperature and comprised of a fatty acid ester of a polyglycerol. The preparation has stable release controlling ability, can be processed to fine granules, granules, capsules, tablets etc., and contributes to reduction of the administration times of the active ingredient and side effects of the ingredient.
REFERENCES:
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patent: 4777050 (1988-10-01), Vadino et al.
patent: 4806337 (1989-02-01), Swipes et al.
patent: 4844907 (1989-07-01), Elger et al.
patent: 4857336 (1989-08-01), Khanna et al.
Patent Abstract of Japan, vol. 8, No. 145, Jul. 6, 1984.
"Physical and Chemical Properties of Calcuim Phospates For Solid State Pharmaceutical Formulations", Carstensen et al., Drug Development & Industrial Pharmacy. 16(7), 1121-1133, 1990.
M. R. Baichwal et al., "The Indian Journal of Pharmacy", Sustained Release Capsules using Polyglycerol Esters, vol. 35, No. 5, Sep.-Oct. 1973, pp. 146-150.
Akiyama Yohko
Horibe Hidetoshi
Yoshioka Minoru
Takeda Chemical Industries Ltd.
Webman Edward J.
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