Sustained-release preparation for AII antagonist, production...

Details Sustained-release preparation for AII antagonist, production... Sustained-release preparation for AII antagonist, production...

2007-11-13

2007-11-13

Kennedy, Sharon E. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S489000, C424S499000

Reexamination Certificate

active

10443308

ABSTRACT:
The present invention is to provide a sustained-release preparation which comprises a compound having angiotensin II antagonistic activity, its pro-drug or their salt, and a biodegradable polymer, and if necessary, a polyvalent metal, and which is highly stable and active and shows angiotensin II antagonistic activity while maintaining circadian rhythm of blood pressure for a long time.

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patent: 5968978 (1999-10-01), Kleemann et al.
patent: 6294197 (2001-09-01), Wagner et al.
patent: 6306826 (2001-10-01), Ross et al.
patent: 6589547 (2003-07-01), Igari et al.
Sustained Release Tablets, Feb. 2001,http://www.boomer.org/c/p1/Ch13/Ch1303.html.

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