Sustained-release pranoprofen preparation

Details Sustained-release pranoprofen preparation Sustained-release pranoprofen preparation

1992-02-04

1993-07-06

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424461, 424462, 424476, 424479, 424480, 424491, 424493, 424494, 424495, 424496, 424497, 424498, 424499, 424500, 424502, 424482, 514963, A61K 916, A61K 954, A61K 958

Patent

active

052252060

ABSTRACT:
A sustained-release pranoprofen preparation is disclosed. The preparation comprises an effective amount of pranoprofen and one or more sustained-release components selected from the group consisting of oily components, water-soluble components, water-insoluble components, and intestinally soluble components. It controls release of pranoprofen and lowers the maximum pranoprofen concentration in blood, maintaining its concentration in blood at a certain level for a long period of time. It reduces risks of side effects and can effectively treat diseases with dosing once or twice a day.

REFERENCES:
patent: 4971805 (1990-11-01), Kitanishi et al.
Chemical Abstracts, vol. 113, No. 10, 84872y, and JP-A-02-088519, Mar. 28, 1990.
Chemical Abstracts, vol. 110, No. 10, 82500q, and JP-A-63-079817, Sep. 4, 1988.
Chemical Abstracts, vol. 106, No. 22, 182682m, and JP-A-62-033116, Feb. 13, 1987.
Chemical Abstracts, vol. 114, No. 24, 235088w, and JP-A-03-041020, Feb. 21, 1991.

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