Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Processes of preparing a desired or intentional composition...
Patent
1984-11-09
1987-03-03
Griffin, Ronald W.
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
Processes of preparing a desired or intentional composition...
424470, 424 81, 514777, A61K 922, A61K 924
Patent
active
046475990
ABSTRACT:
The invention provides a method for preparing sustained release tablets comprising a hydrophilic polymer matrix, which amounts to at least 10% by weight of the composition, consisting of a 5:1-1:5 weight to weight ratio mixture of a VP-VA copolymer and of an acrylic acid homopolymer, cross-linked with polyallyl saccharose.
The method of manufacturing of sustained release tablets according to the invention can be accomplished in two ways: either by manufacturing the granulate containing the active ingredient, or by supplementing the matrix granulate containing no active ingredient with the suitable amount of the active ingredient.
The latter variant involves the advantage of a possible separation of large-scale manufacturing of pharmacons and that of a generally applicable retardizing system, the composition and, consequently, the retardizing ability of which can optionally be modified in accordance with the properties of the active ingredient(s) to be formulated.
REFERENCES:
patent: 2909462 (1959-10-01), Warfield et al.
patent: 3362881 (1968-01-01), Eberhardt et al.
patent: 3458622 (1969-07-01), Hill
patent: 3590117 (1971-06-01), Christenson et al.
patent: 3634584 (1972-01-01), Poole
patent: 3870790 (1975-03-01), Lowey et al.
patent: 4252786 (1981-02-01), Weiss et al.
patent: 4351825 (1982-09-01), Sothmann et al.
patent: 4524060 (1985-06-01), Mughal et al.
patent: 4557925 (1985-12-01), Lindahl et al.
Bezzegh Denes
Bor Ilona
Fekete Pal
Fellner Erzsebet
Toth Zoltan
Egyt Gyogyszervegyeszeti Cyar
Griffin Ronald W.
LandOfFree
Sustained release pharmaceutical tablets and process for the pre does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Sustained release pharmaceutical tablets and process for the pre, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sustained release pharmaceutical tablets and process for the pre will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1017069