Sustained release pharmaceutical compositions

Details Sustained release pharmaceutical compositions Sustained release pharmaceutical compositions

1989-06-26

1990-11-27

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424468, A61K 920

Patent

active

049734709

ABSTRACT:
A sustained release oral pharmaceutical composition consists essentially of a recompressed mixture of a water-sensitive pharmaceutical agent, a high molecular weight hydrophilic cellulose polymer, and a lubricant. The mixture is compressed into a unitary mass, comminuted, and recompressed into tablets without the use of solvents.

REFERENCES:
patent: 2395881 (1969-07-01), Hamada
patent: 3133863 (1964-05-01), Tansey
patent: 3758679 (1973-09-01), Seidler
patent: 3773920 (1973-11-01), Nakamoto et al.
patent: 4547358 (1985-10-01), David et al.
patent: 4556678 (1985-12-01), Hsiao
patent: 4590062 (1986-05-01), Jang
patent: 4652442 (1987-03-01), Hopfgartner et al.
patent: 4786508 (1988-11-01), Ghebre-Sellassie et al.

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