Sustained release pharmaceutical composition of diltiazem

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

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424458, 424461, 424462, 424465, 424480, 424482, 424495, 427 3, A61K 916, A61K 958, A61K 962

Patent

active

051126214

ABSTRACT:
A sustained-release pharmaceutical composition which comprises microparticles comprising an active principle, said microparticles being coated with a coating mixture comprising ethyl cellulose and an acrylic resin which is a polymerizate of acrylic and methacrylic ester, having a molecular weight of at least 100,000 and comprising units of formula: ##STR1## wherein: R.sub.1 is hydrogen or methyl,

REFERENCES:
patent: 4533674 (1985-08-01), Schmidt et al.
patent: 4775536 (1988-10-01), Patel
patent: 4780318 (1988-10-01), Appelgren et al.
patent: 4800087 (1989-01-01), Mehta
Patent Abstracts of Japan, vol. 11, No. 184, Jun. 12, 1987, JP-A-62 5915.
Patent Abstracts of Japan, vol. 11, No. 47, Feb. 13, 1987, JP-A-61 212517.

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