Sustained release pharmaceutical composition

Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...

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424 20, 424 21, A61K 952, A61K 954, A61K 958

Patent

active

041384750

ABSTRACT:
Sustained release pharmaceutical composition consisting of a hard gelatine capsule containing film coated spheroids, the spheroids comprising propranolol, or a pharmaceutically-acceptable salt thereof, in admixture with non-water-swellable microcrystalline cellulose, and the said spheroids having a film coat comprising ethylcellulose optionally together with hydroxypropyl methylcellulose and/or a plasticizer.

REFERENCES:
patent: 2853420 (1958-09-01), Lowey
patent: 2887440 (1959-05-01), Greminger et al.
patent: 2921883 (1960-01-01), Reese et al.
patent: 2928770 (1960-03-01), Bardani
patent: 3146168 (1964-08-01), Battista
patent: 3247066 (1966-04-01), Milosovich
patent: 3400185 (1968-09-01), Kohnle et al.
patent: 3492397 (1970-01-01), Peters et al.
patent: 3835221 (1974-09-01), Fulborth et al.
patent: 3917813 (1975-11-01), Pederson
Windholz et al., Merck Index 9th Ed. 1976, Merck & Co., Rahway, N. J. #7628, p. 1016, entry "Propranolol".

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