Sustained release pharmaceutical capsules

Details Sustained release pharmaceutical capsules Sustained release pharmaceutical capsules

1977-09-19

1978-11-21

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 19, A61K 952, A61K 926

Patent

active

041266722

ABSTRACT:
Sustained release pharmaceutical capsules suitable for oral administration and particularly suitable for sustained release therapy with certain benzodiazepines, e.g. chlordiazepoxide and diazepam, are disclosed. The formulation contained in the disclosed capsules is hydrodynamically balanced to be buoyant in gastric fluid thereby remaining buoyant in the gastric fluid until substantially all of the medicament therein has been released.

REFERENCES:
patent: 3065143 (1962-11-01), Christenson et al.
patent: 3122474 (1964-02-01), Carstensen
patent: 3140978 (1964-07-01), Zentner
patent: 3365365 (1968-01-01), Butler et al.
patent: 3418999 (1968-12-01), Davis
patent: 3427378 (1969-02-01), Henderson et al.
patent: 3444290 (1969-05-01), Wai
patent: 3449489 (1969-06-01), Gaunt
patent: 3555151 (1971-01-01), Kaplan et al.
patent: 3574820 (1971-04-01), Johnson et al.
C.A. 60 #10484g(1964), 73 #69844c(1970), 76 #121938q(1972), 81 #54444p(1974).

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