Sustained-release percutaneous preparations

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424447, 424449, A61F 1302

Patent

active

048897213

ABSTRACT:
Sustained-release percutaneous preparations which have at least two adhesive layers and in which a drug is contained in the layer farthest from the skin and a solid powder is dispersed in an adhesive layer other than the layer farthest from the skin provide slow release of the drug. By varying the kind and concentration of the solid powder, the rate of release of the drug from the preparations can be controlled.

REFERENCES:
patent: 3742951 (1973-07-01), Zaffaroni
patent: 3982946 (1976-09-01), Maekawa
patent: 4432802 (1984-02-01), Harata et al.
patent: 4443497 (1984-04-01), Samejima et al.
patent: 4540701 (1985-08-01), Ueda et al.
patent: 4575548 (1986-03-01), Ueda
patent: 4749574 (1988-06-01), Ueda et al.
Chemical Abstracts, vol. 100, #161803n (1986).
Search Report for European Patent Application 88 11 1816.
Dictionaire `Vidal`, 60th Ed., 1984, p. 1439, Paris, FR Column 2: "Trintrine 10 mg-6.5 mg-2.5 mg Laleuf".

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