Sustained release ophthalmic drug dosage

Details Sustained release ophthalmic drug dosage Sustained release ophthalmic drug dosage

1979-05-09

1981-06-02

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 81, 424181, 424273R, 424283, 424300, 424324, 424331, A61K 3174, A61K 3178, A61K 3171, A61K 3135

Patent

active

042711436

ABSTRACT:
The present invention is directed to an aqueous dispersion of an ophthalmic drug and a high molecular weight polymer which forms a highly viscous gel and can be used to prolong the duration of activity of the ophthalmic drug when the gel is applied into the conjunctival sac of the eye. The ophthalmic drug-containing gel composition has prolonged retention time in the eye and remains in contact with the surface of the eye for an extended period of time.

REFERENCES:
patent: 2707777 (1955-03-01), Feinstein et al.
patent: 2798053 (1957-07-01), Brown
patent: 3214338 (1965-10-01), Ehrlich
patent: 3947573 (1976-03-01), Rankin
patent: 3966902 (1976-06-01), Chromecek
patent: 4003991 (1977-01-01), Krohn et al.
J. Pharm. Sciences 67(9), pp. 1280-1283, (1978), Schoenwald et al.

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