Sustained release ophthalmic compositions containing water solub

Details Sustained release ophthalmic compositions containing water solub Sustained release ophthalmic compositions containing water solub

1997-11-04

2000-12-12

Azpuru, Carlos

Drug, bio-affecting and body treating compositions

Topical body preparation containing solid synthetic organic...

Ophthalmic preparation

514912, 514913, 514914, A61K 3174

Patent

active

06159458&

ABSTRACT:
An ophthalmic composition that provides sustained release of a water soluble medicament is formed comprising a crosslinked carboxy-containing polymer, a medicament, a sugar and water. The composition has a pH of at least 6.7 but a viscosity of from about 1000 to 5000 cps.

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Thermes er al., "Bioadhesion: The Effect of Polyacrylic Acid on the Ocular Bioavailability of Timolol," Internantional Journal of Pharmaceutics, 81:59-65 (1992).

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