Sustained release ophthalmic antibiotic compositions

Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Ophthalmic preparation

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514 23, 514 25, 514 82, 514 54, 514192, A61K 3170, A61K 3174

Patent

active

059852593

ABSTRACT:
An improved method of sterilizing the field of surgery prior to an ophthalmic surgical procedure is described. The invention eliminates the need for painfull and potentially traumatic injections of antibiotics by utilizing sustained release compositions which allow the antibiotics contained therein to penetrate deeply into the eye, thereby ensuring a sterile field of surgery during intraocular surgical procedures. The compositions may also be utilized to prevent post-surgical infections.

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Hobden, J. A., et al, "Quinolones in Collagen Shields to Treat Aminoglycoside-resistant Pseudomonal Keratitis", Inves. Ophthalmol. Vis. Sci., vol. 31, No. 11, pp. 2241-2243 (Nov. 1990).
Mondino, B.J., "Collagen Shields", American Journal of Ophthalmology, vol. 112, No. 5, pp. 587-590 (Nov. 1991).

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