Sustained release of peptides from pharmaceutical compositions

Details Sustained release of peptides from pharmaceutical compositions Sustained release of peptides from pharmaceutical compositions

1995-03-08

1997-01-21

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424422, 424484, 424488, A61K 920

Patent

active

055957609

ABSTRACT:
The invention features a method of administering a peptide to a patient and delivering the peptide continuously over an extended period of time of at least three days by obtaining a solid pharmaceutical composition including a soluble, gelable salt of the peptide and up to 30 percent, by weight, of a pharmaceutically acceptable, soluble, monomeric carrier, and parenterally administering the solid composition to the patient in one injection, wherein the solid composition automatically forms a gel after interaction with the patient's bodily fluids and releases the peptide continuously within the patient over an extended period of at least three days.

REFERENCES:
patent: 3773919 (1973-11-01), Boswell et al.
patent: 5134122 (1992-07-01), Orsolini
patent: 5225205 (1993-07-01), Orsolini
patent: 5279608 (1994-01-01), Cherig Cheikh
Search Report, Mar. 1996, WOX.
Database WPI, Section Ch, Week 9242, Derwent Publications Ltd., London, GB; Class B04, An 92-124827 & JP-A-04 244 031, (ZH Kankoku Kagaku Gijutsu Kenk), 1 Sep. 1992 (See Abstract).
Eckhardt et al., "Effect of Freezing on Aggregation of Human Growth Hormone", Pharm. Res. 8:1360-64 (1991).
Powell et al., "Peptide Liquid Crystals: Inverse Correlation of Kinetic Formation . . . ", Pharm. Res. 9:1352-54, (1994).
Wan et al., Pharm. Res. 11 (Supp. 10); Abstracts: PDD 7275 at p. S-243, and PDD 7466 at p. S-291 (1994).

Affiliated with

Also associated with

Rating

Sustained release of peptides from pharmaceutical compositions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Sustained release of peptides from pharmaceutical compositions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sustained release of peptides from pharmaceutical compositions will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2322548