Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2004-12-21
2010-06-01
Weber, Jon P (Department: 1657)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
Reexamination Certificate
active
07727554
ABSTRACT:
The present invention is a composition composed of a therapeutic agent encapsulated in a copolymer of an N-alkylacrylamide, a vinyl monomer, and a polyethylene glycol (PEG) conjugate and a method for using the same in the treatment or prevention of a disease or condition.
REFERENCES:
patent: 6322817 (2001-11-01), Maitra et al.
patent: 6759431 (2004-07-01), Hunter et al.
patent: 2003/0054042 (2003-03-01), Liversidge et al.
patent: 2003/0199425 (2003-10-01), Desai et al.
Edelman et al., “Effect of controlled adventitial heparin delivery on smooth muscle cell proliferation following endothelial injury”, Proc. Natl. Acad. Sci. USA 1990 87:3773-3777.
Edelman et al., “Perivascular and intravenous administration of basic fibroblast growth factor: Vascular and solid organ deposition”, Proc. Natl. Acad. Sci. USA 1993 90:1513-1517.
Edelman et al., “Contrasting Effects of the Intermittent and Continuous Administration of Heparin in Experimental Restenosis”, Circulation 1994 89:770-776.
Garcia et al., “Intraoperative Intra-Arterial urokinase Infusion as an Adjunct to Fogarty Catheter Embolectomy in Acute Arterial Occlusion”, Surgery, Gynecology & Obstetrics 1990 171:201-205.
Gupta et al., “Ketorolac entrapped in polymeric micelles:preparation, characterisation and ocular anti-inflammatory studies”, International Journal of Pharmaceutics 2000 209:1-14.
Labhasetwar et al., “Nanoparticle drug delivery system for restenosis”, Advanced Drug Delivery Reviews 1997 24:63-85.
Lanza et al., “Targeted Antiproliferative Drug Delivery to Vascular Smooth Muscle Cells With a Magnetic Resonance Imaging Nanoparticle Contrast Agent”, Circulation 2002 106:2842-2847.
Nathan et al., “Tissue engineered perivascular endothelial cell implants regulate vascular injury”, Proc. Natl. Acad. Sci. USA 1995 92:8130-8134.
Okada et al., “Localized Release of Perivascular Heparin Inhibits Intimal Proliferation after Endothelial Injury without Systemic Anticoagulation”, Neurosurgery 1989 25(6):892-898.
Villa et al., “Local Delivery of Dexamethasone for Prevention of Neointimal Proliferation in a Rat Model of balloon Angioplasty”, J. Clin. Invest. 1994 93:1243-1249.
Villa et al., “Effects of Antisense c-mybOligonucleotides on Vascular Smooth Muscle Cell Proliferation and Response to Vessel Wall Injury”, Circ. Res. 1995 76:505-513.
Labhasetwar Vinod D.
Reddy Maram K.
Sahoo Sanjeeb K.
Board of Regents of the University of Nebraska by and Behalf of
Dann Dorfman Herrell and Skillman
Hagan Patrick J.
Singh Satyendra K
Weber Jon P
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