Sustained release ibuprofen formulation including a core of ibup

Details Sustained release ibuprofen formulation including a core of ibup Sustained release ibuprofen formulation including a core of ibup

1987-07-30

1990-02-13

Bell, Mark L.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424462, 424470, 424494, 424497, A61K 916, A61K 924

Patent

active

049005588

ABSTRACT:
The present invention provides a sustained release .alpha.methyl-4-(2-methylpropyl)benzene acetic acid (Ibuprofen) formulation comprising sufficient granules to provide a predetermined dose or number of doses of Ibuprofen, each granule having a diameter between 0.5 and 2.0 mm and comprising:

REFERENCES:
patent: 4138475 (1979-02-01), McAinsh et al.
patent: 4205060 (1980-05-01), Monsimer et al.
patent: 4343789 (1982-08-01), Kawata et al.
patent: 4555399 (1985-11-01), Hsigo
patent: 4578264 (1986-03-01), Stricker et al.
patent: 4695591 (1987-09-01), Hanna et al.
patent: 4710384 (1987-12-01), Rotman
A. T. Florence and D. Attwood, Physicochemical Principles of Pharmacy, pp. 319 to 324 (MacMillan 1988).
Edited by E. A. Rawlins, Bentley's Textbook of Pharmaceutics, Eighth Edition, pp. 661-62, Published by Bailliere Tindall, London (1977).

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