Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...
Patent
1982-09-28
1984-01-31
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Identification or warning feature
Taste or smell or chemical irritation to the eye, nose, or...
A61K 922, A61K 924, A61K 932
Patent
active
044289251
ABSTRACT:
Glycerol trinitrate is delivered orally in a sustained release dosage form. The dosage form is for oral administration and comprises a core containing the drug and a coating of an expandable lattice, said expandable lattice permitting the passage of water therethrough but which under conditions of high pressure is expanded to a state whereby molecules of the drug are permitted to pass therethrough, said expandable lattice retaining its structural integrity, said dosage form when contacted with the aqueous medium of the gastro-intestinal tract taking up water in said core through passage of water through said expandable lattice, whereby an osmotic pressure is built up causing said expandable lattice to expand responsive to said osmotic pressure, the drug being permitted to escape through the resultant expanded lattice structure of said expandable lattice.
REFERENCES:
patent: 2693438 (1954-11-01), Ward
patent: 3096248 (1963-07-01), Rudzki
patent: 3832470 (1974-08-01), Russek
patent: 3935326 (1976-01-01), Groppenbacher et al.
patent: 3951821 (1976-04-01), Davidson
patent: 4060598 (1977-11-01), Groppenbacher et al.
patent: 4235870 (1980-11-01), Leslie
patent: 4248856 (1981-02-01), Guley et al.
patent: 4248857 (1981-02-01), DeNeale et al.
patent: 4248858 (1981-02-01), Guley et al.
patent: 4249531 (1981-02-01), Heller et al.
patent: 4330338 (1982-05-01), Banker
Key Pharmaceuticals, Inc.
Rose Shep K.
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