Sustained-release formulations

Details Sustained-release formulations Sustained-release formulations

1988-10-20

1991-10-08

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424466, 424480, A61K 932, A61K 946, A61K 736

Patent

active

050553062

ABSTRACT:
A granular sustained-release formulation of a pharmacologically active substance presented in the form of a tablet, said tablet comprising sufficient granules to provide a predetermined dose or number of doses of the pharmacologically active substance and effervescent or water-dispersible ingredients, each of said granules having a diameter of preferably between 0.5 and 2.5 mm and comprising:

REFERENCES:
patent: 3131123 (1964-04-01), Masquelier
patent: 3961041 (1976-06-01), Nishimura et al.
patent: 4147768 (1979-04-01), Shaffer et al.
patent: 4348091 (1984-03-01), Gruber et al.
patent: 4765988 (1988-08-01), Sonobe et al.
patent: 4786505 (1988-11-01), Lovgren et al.
patent: 4832956 (1989-05-01), Gergely et al.
patent: 4844905 (1989-07-01), Ichikawa et al.
"Eudragit.RTM. NE30D" Technical Application Pamphlet, Aqueous Dispersion for Controlled-Release Permeable Film Coatings.

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