Sustained-release formulation of methylphenidate

Details Sustained-release formulation of methylphenidate Sustained-release formulation of methylphenidate

1996-07-15

1999-02-23

Schofer, Joseph L.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

424468, 424489, 424441, 424470, A61K 900

Patent

active

058740902

ABSTRACT:
The subject invention pertains to a sustained-release formulation of d-threo-methylphenidate (dtmp). The subject invention also pertains to methods for treating disorders using a sustained-release formulation comprising d-threo-methylphenidate.

REFERENCES:
patent: 2507631 (1950-05-01), Hartmann et al.
patent: 2838519 (1958-06-01), Rometsch
patent: 2957880 (1960-10-01), Rometsch
patent: 4192827 (1980-03-01), Mueller et al.
patent: 5583140 (1996-12-01), Bencherif et al.
Patrick, K. S. et al. (1987) "Pharmacology of the Enantiomers of threo-Methylphenidate" The Journal of Pharmacology and Experimental Therapeutics 241(1):152-158.
Eckerman, D.A. et al. (1991) "Enantioselective Behavioral Effects of threo-Methylphenidate in Rats" Pharmacology Biochemistry & Behavior 40:875-880.

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