Sustained release formulation containing three different types o

Details Sustained release formulation containing three different types o Sustained release formulation containing three different types o

1997-12-05

2000-07-04

Spear, James M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424469, 424470, 5147723, 514779, 514781, 514782, 514960, 514961, 514964, 514965, A61K 922

Patent

active

06083532&

ABSTRACT:
Depot drug formulations include the pharmaceutical itself and a three component release rate controlling matrix composition. The three components of the matrix composition are (1) a pH dependent gelling polymer such as an alginate component, (2) an enteric polymer component, such as Eudragit.RTM. L or S, and (3) a pH independent gelling polymer, such as hydroxy propyl methyl cellulose or polyethylene oxide. The drug release rate can be adjusted by changing the amount of one or more of these components of the composition.

REFERENCES:
patent: 3261859 (1966-07-01), Dengel
patent: 4157394 (1979-06-01), Fleckenstein et al.
patent: 4461759 (1984-07-01), Dunn
patent: 4654372 (1987-03-01), Marcoux
patent: 4697035 (1987-09-01), Kisielowski et al.
patent: 4708874 (1987-11-01), De Haan et al.
patent: 4753803 (1988-06-01), Stephens et al.
patent: 4792452 (1988-12-01), Howard et al.
patent: 4798811 (1989-01-01), Lehmann et al.
patent: 4800081 (1989-01-01), Albrecht et al.
patent: 4832958 (1989-05-01), Baudier et al.
patent: 4859469 (1989-08-01), Baudier et al.
patent: 4863742 (1989-09-01), Panoz et al.
patent: 4952672 (1990-05-01), Gremm et al.
patent: 4981871 (1991-01-01), Abelson
patent: 5047235 (1991-09-01), Lossnitzer et al.
patent: 5089502 (1992-02-01), Sudilovsky et al.
patent: 5128142 (1992-07-01), Mulligan et al.
patent: 5132119 (1992-07-01), Lee
patent: 5132295 (1992-07-01), Balz et al.
patent: 5169639 (1992-12-01), Baichwal et al.
patent: 5230901 (1993-07-01), Einig et al.
patent: 5252337 (1993-10-01), Powell
patent: 5350771 (1994-09-01), Pang et al.
Excerpts from the Handbook of Pharmaceutical Excipients, Second Edition, published by the American Pharmaceutical Association.

Affiliated with

Also associated with

Rating

Sustained release formulation containing three different types o does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Sustained release formulation containing three different types o, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sustained release formulation containing three different types o will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1483655