Sustained release formulation

Details Sustained release formulation Sustained release formulation

1997-10-09

1999-07-13

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424468, 424469, A61K 914

Patent

active

059223561

ABSTRACT:
The present invention relates to a sustained release formulation used for treatment or prevention of the diseases, which contains a therapeutically effective substance as an active ingredient, collagen as a drug carrier, and glycosaminoglycan as an additive. The formulation allows controlled release of the therapeutically effective substance.

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patent: 5385738 (1995-01-01), Yamahira et al.
patent: 5693341 (1997-12-01), Schroeder et al.
Murata et al., "Additive effect of chondroitin sulfate and chitosan on drug release from calcium-induced alginate gel beads," Journal of Controlled Release, pp. 101-108, No. 38 (1996).
B. Alberts et al., Molecular Biology of the Cell, 692-701 (1983) J. Scott, Biochem J, 252:313-323 (1988).
A.K. Garg, Biomaterials, 10:413-419 (1989).

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