Sustained release drug formulations

Details Sustained release drug formulations Sustained release drug formulations

1996-01-16

1999-11-09

Wortman, Donna C.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

514 2, 514 15, 514 16, 514 26, 514169, 514177, 514182, A61K 908

Patent

active

059809450

ABSTRACT:
A sustained release drug formulation including: a drug; a biodegradable polymer which is insoluble in water; and an oil vehicle in which both the drug and the polymer are dissolved. The oil vehicle contains 10-100% by volume a pharmaceutically acceptable oil and 0-90% by volume a pharmaceutically acceptable liquid carrier for the drug or the polymer.

REFERENCES:
patent: 3773919 (1973-11-01), Boswell et al.
patent: 4678809 (1987-07-01), Phillips
patent: 4707470 (1987-11-01), Kirsch et al.
patent: 4767628 (1988-08-01), Hutchinson
patent: 4938763 (1990-07-01), Dunn et al.
patent: 5213812 (1993-05-01), Ruiz
patent: 5470582 (1995-11-01), Supersaxo et al.
patent: 5576016 (1996-11-01), Amselem et al.
patent: 5582591 (1996-12-01), Cheikh
patent: 5648096 (1997-07-01), Gander et al.
Millest et al., "Sustained Release of Salmon Calcitonin In Vivo from Lact: Glycolide Copolymer Depots", Calcif Tissue Int. 52:361-364, 1993.

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