Sustained release drug delivery system suitable for oral adminis

Details Sustained release drug delivery system suitable for oral adminis Sustained release drug delivery system suitable for oral adminis

1997-08-18

1999-03-23

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424461, 424490, 424494, 424495, 424497, A61K 924

Patent

active

058856161

ABSTRACT:
A single bead drug delivery system suitable for oral administration with multiply layered drug and polymer compartments can provide a two-step release of active agent to facilitate an immediate yet sustained drug delivery over a 24 hour period following oral administration with minimized variance between peak and trough levels of therapeutic drug amounts.

REFERENCES:
patent: 4894240 (1990-01-01), Geoghegan et al.
patent: 5320853 (1994-06-01), Noda et al.
patent: 5439689 (1995-08-01), Hendrickson et al.
patent: 5474786 (1995-12-01), Kotwal et al.
{711} Dissolution; USP 23; Physical Tests {711} 1791-1794, 2185,3208-3209, 2577-2578, 3794-3495, 2833-2834.
{724} Drug Release; USP 23; Physical Tests 1793-1799,2534-2536, 2709-2715, 3012-3017, 3209-3215, 3468-3474.

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