Sustained release dosage form for use with tissues of the oral c

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424435, A61F 702

Patent

active

048897205

ABSTRACT:
A drug reservoir containing an active substance such as a drug is formed on an adhesive layer which can adhere to an oral mucosal membrane. A polymer, which does not dissolve with saliva, is further coated on the drug reservoir as a drug release controlling layer to form an entire oral cavity sustained release dosage form. A drug impermeable layer can be formed between the adhesive layer and the drug reservoir.

REFERENCES:
patent: 688446 (1901-12-01), Stempel
patent: 3536809 (1970-10-01), Applezweig
patent: 3598122 (1971-08-01), Zaffaroni
patent: 3731683 (1973-05-01), Zaffaroni
patent: 3996934 (1976-12-01), Zaffaroni
patent: 4226848 (1980-10-01), Nagai et al.
patent: 4704119 (1987-11-01), Shaw et al.

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