Surgery – Controlled release therapeutic device or system – Osmotic or diffusion pumped device or system
Patent
1981-01-19
1983-05-03
Rosenbaum, C. Fred
Surgery
Controlled release therapeutic device or system
Osmotic or diffusion pumped device or system
424 21, A61M 700, A61D 700
Patent
active
043817807
ABSTRACT:
A device and a method for the prolonged administration of controlled amounts of a substance are disclosed. In one embodiment, the device is disclosed for the prolonged administration of dosages of a therapeutic, additive, or nutrient substance into the reticulorumen of a ruminant, comprising a body having an interior chamber, at least one end of said chamber open to the exterior of said body, said body made from a material which maintains its integrity in the reticulorumen environment, a plurality of degradable, such as cellulosic, partitions within said interior chamber connected to or fitting closely against the inner walls of said body, said partitions dividing said interior chamber into a series of compartments, each compartment containing a dosage of the therapeutic, additive or nutrient substance, said partitions arranged in an order to be degraded sequentially upon exposure to the reticulorumen environment thereby releasing sequentially the dosages of the substance into the reticulorumen, and retaining means provided by said body to retain the device within the reticulorumen of the ruminant.
REFERENCES:
patent: 4034756 (1977-07-01), Higuchi et al.
patent: 4165998 (1979-08-01), Adams et al.
patent: 4217898 (1980-08-01), Theeuwes
patent: 4249531 (1981-02-01), Heller et al.
patent: 4290426 (1981-09-01), Luschen et al.
patent: 4308250 (1981-12-01), Griffin et al.
Research Corporation
Rosenbaum C. Fred
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