Sustained release compositions and a method of preparing pharmac

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills

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424451, 424452, 424457, 424464, 424469, 424470, 424484, 424485, 424486, 424487, 424488, 424489, A61K 914, A61K 916, A61K 926, A61K 948

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active

061624675

ABSTRACT:
A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form agglomerates, breaking the agglomerates to give controlled release particles and optionally continuing the mechanical working with the optional addition of a low percentage of the carrier or diluent.

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