Sustained release composition and method utilizing xanthan gum a

Details Sustained release composition and method utilizing xanthan gum a Sustained release composition and method utilizing xanthan gum a

1992-03-25

1994-03-08

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424457, 424469, 424489, 424470, A61K 948

Patent

active

052925340

ABSTRACT:
A compacted sustained release composition for delivering a drug as an active ingredient to the gastro-intestinal tract comprises an effective amount of the active ingredient in mixture with xanthan gum, the active ingredient comprising in excess of 40 percent by weight of the total of the active ingredient and the xanthan gum, the mixture being in the form of a unit dose in capsule or tablet form. In addition to niacin, the active ingredient may be an analgesic, antipyretic, anti-inflammatory agent, vitamin, electrolyte replenisher, decongestant, antihistamine, and useful bacteriological organisms for the gastro-intestinal tract.

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patent: 5051261 (1991-09-01), McGinity
patent: 5096714 (1992-03-01), Kuhrts
patent: 5120762 (1992-06-01), Hanaoka et al.

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