Sustained production of recombinant gamma interferon using an Ep

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4352402, 43524026, 435320, 424 855, C12P 2100, C12N 1500, C12N 500

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049390880

ABSTRACT:
A recombinant DNA expression vector comprising an Epstein-Barr virus origin of replication, an EBNA-1 gene, a selectable marker expression cassette and a human gamma interferon expression cassette comprising a promoter region, an open reading frame encoding human gamma interferon and a polyadenylation region; a mammalian host cell transformed by said vector; and a process for producing human gamma interferon using said transformed mammalian host cell.

REFERENCES:
patent: 4686186 (1987-08-01), Sugden

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