Sustained delivery of leuprolide using an implantable system

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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Details

424423, 424424, 424473, 6048911, A61F 1300, A61F 200, A61F 922

Patent

active

057283966

ABSTRACT:
The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.

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