Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1994-02-10
1998-07-07
Lukton, David
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 15, 514 16, 514 17, 514 18, 424409, 424417, 424490, 424491, A61K 3804, A61K 952
Patent
active
057768854
ABSTRACT:
A pharmaceutical composition for the sustained release of a peptide wherein the composition includes a polylactide polymer, a polymer of lactic acid and glycolic acid, or a mixture of such polymers and a therapeutically active peptide in the form of its pamoate, tannate or stearate salt. The composition when placed in an aqueous physiological environment releases the peptide in a continuous manner for a period of at least about one week.
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Chang, "Biodegradable Semipermeable Microcapsules Containing Enzymes, Hormones, Vaccines and Other Biologicals", J. Bioeng. 1 (1976) p. 25.
Langer, "Controlled Release of Macromolecules", Chemtech Feb. 1982 pp. 98-105.
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Chemical Abstracts, vol. 107, No. 13, Abstract 109765g (1987).
Deghenghi Romano
Mauvernay Rolland-Yves
Orsolini Piero
Debio Recherche Pharmaceutique SA
Lukton David
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