Suspension of loteprednol etabonate for ear, eye, or nose treatm

Details Suspension of loteprednol etabonate for ear, eye, or nose treatm Suspension of loteprednol etabonate for ear, eye, or nose treatm

1993-10-25

1996-07-30

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424437, 424434, 5147722, 5147725, 514778, 514914, 5147723, 514937, A61K 910, A61K 4732, A61K 4736

Patent

active

055409300

ABSTRACT:
The invention provides novel compositions of matter containing water-insoluble steroid drugs suitable for therapeutic use. The invention provides stable aqueous suspensions of water-insoluble steroid drugs of particle sizes of .ltoreq.15 .mu.m which remain in such a state so as to allow for immediate suspension, when desired, even after extended periods of settling.

REFERENCES:
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patent: 4383992 (1983-05-01), Lipari
patent: 4409205 (1983-10-01), Shively
patent: 4602026 (1986-07-01), Awata et al.
patent: 4710495 (1987-12-01), Bodor
patent: 5089482 (1992-02-01), Hermens et al.
patent: 5149693 (1992-09-01), Cagle et al.
patent: 5277901 (1994-01-01), Vigh et al.
patent: 5424078 (1995-06-01), Dziabo et al.
CA117: 178175, Albertha et al., 1991.
Remington's Pharmaceutical Sciences, 18th Edition, p. 1587-1592, 1990.

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