Suspendible composition and process for preparing the same

Details Suspendible composition and process for preparing the same Suspendible composition and process for preparing the same

1993-07-27

1994-11-29

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424427, 514912, 514937, 514975, 514970, 514885, 514952, A61K 910, A61K 914

Patent

active

053688651

ABSTRACT:
A suspendible composition comprising a tricyclic compound such as FK 506 substance which is 17-allyl-1,14-dihydroxy-12-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylviny 1]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1 .0.sup.4,9 ]octacos-18-ene-2,3,10,16-tetraone, or the like, and a pharmaceutically acceptable surfactant, which can be used as an orally administrable agent or eye drops and is useful for treating various diseases.

REFERENCES:
Transplantation, vol. 45, No. 1, pp. 206-209, Jan. 1988, N. Inamura, et al., "Prolongation of Skin Allograft Survival in Rats by a Novel Immunosuppressive Agent, FK506".
ACTA Societatis Ophthalmologicae Japonicae, p. 152, Feb. 20, 1988, (with partial English translation).

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