Survivin inhibitors

Details Survivin inhibitors Survivin inhibitors

2011-03-22

2011-03-22

Morris, Patricia L (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07910742

ABSTRACT:
Compounds that inhibit survivin, compositions containing the compounds and methods of treating diseases in which survivin is unregulated or overexpressed are disclosed.

REFERENCES:
Balant et al., “Metabolic Considerations, etc.,”Burger's Medicinal Chemistry, 5th ed., 1, Wolff ed. NY: John Wiley & Sons, 1995, pp. 949-982.
A. Burkle, et al., “Ageing and PARP”,Pharmacological Research, 52: 93-99 (2005).
A. Chiarugi, et al., “Poly(ADP-ribosyl)ation and Stroke”,Pharmacological Research, 52: 15-24 (2005).
S. Cuzzocrea, et al., “Role of Poly(ADP-ribose) Glycohydrolase (PARG) in Shock, Ischemia and Reperfusion”,Pharmacological Research, 52: 100-108 (2005).
S. Cuzzocrea, et al., “Shock, Inflammation and PARP”,Pharmacological Research, 52: 72-82 (2005).
K. Devalaraja-Narashimha, et al. “Poly(ADP-ribose) Polymerase-Medicated Cell Injury in Acute Renal Failure”,Pharmacological Research, 52: 44-59 (2005).
G. Graziani, et al., “Clinical Perspectives of PARP Inhibitors”,Pharmacological Research, 52: 109-118 (2005).
G. Graziani, et al., “PARP-1 Inhibition to Treat Cancer, Ischemia, Inflammation”,Pharmacological Research, 52: 1-4 (2005).
D.W. Koh, et al. “Mediation of Cell Death by Poly (ADP-ribose) Polymerase-1”,Pharmacological Research, 52: 5-14 (2005).
C. Szabo, et al., “Cardioprotective Effects of Poly(ADP-ribose) Polynerase Inhibition”,Pharmacological Research, 52: 34-43 (2005).
C. Szabo, et al., “Roles of Poly(ADP-ribose) Polymerase Activiation in the Pathogenesis of Diabetes Mellitus and its Complications”,Pharmacological Research, 52: 60-71 (2005).
L. Tentori, et al., “Chemopotentiation by PARP Inhibitors in Cancer Therapy”,Pharmacological Research, 52: 25-33 (2005).
L. Virag, et al., “Poly(ADP-ribosyl)ation in Asthma and Other Lung Diseases”,Pharmacological Research, 52: 25-33 (2005).

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