Survival motor neuron (SMN) gene: a gene for spinal muscular atr

Details Survival motor neuron (SMN) gene: a gene for spinal muscular atr Survival motor neuron (SMN) gene: a gene for spinal muscular atr

1995-10-19

2000-06-27

Caputa, Anthony C.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

4353201, 536 231, 536 235, 536 241, 536 2431, C12N 1512, C12N 1563, C12N 1585

Patent

active

060805773

ABSTRACT:
The present invention relates to the discovery of the human survival motor-neuron gene or SMN gene which is a chromosome 5-SMA (Spinal Muscular Atrophy) determining gene. The present invention further relates to the nucleotide sequence encoding the SMN gene and corresponding amino acid sequence, a vector containing the gene encoding the SMN protein or a DNA sequence corresponding to the gene and transformant strains containing the SMN gene or a DNA sequence corresponding to the gene.

REFERENCES:
Cross et al. Nature Genetics 6 (1994) 236-244.
Das et al. J. of Biological Chemistry 260 (1985) 6240-6247.
Stratagene Product Catalog (1991) p. 66.

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