Surgical sutures of unsymmetrically substituted 1,4-dioxane-2,5-

Details Surgical sutures of unsymmetrically substituted 1,4-dioxane-2,5- Surgical sutures of unsymmetrically substituted 1,4-dioxane-2,5-

1975-03-14

1976-06-01

Trapp, Lawrence W.

Surgery

Truss

Pad

A61L 1700

Patent

active

039601528

ABSTRACT:
Unsymmetrically 3,6-substituted 1,4-dioxane-2,5-diones may be polymerized to give living-tissue absorbable, hydrolytically degradable surgically useful polymers. These polymers have predominantly regular rather than random spacings of side chains, may be stereoregular and tend toward higher crystallinity than randomly sequenced polymers. A polymer of 3-methyl-1,4-dioxane-2,5-dione has the same empirical formula as an equimolecular copolymer of lactic and glycolic acid but has unique physical properties resulting from its more regular steric configuration. Polymers and copolymers of 3- and 3,6-unsymmetrically substituted 1,4-dioxane-2,5-diones have surgically useful mechanical properties. On implantation, in living mammalian tissue, the polymers are absorbed, and replaced by living tissue.

REFERENCES:
patent: 3755558 (1973-08-01), Scribner
patent: 3772420 (1973-11-01), Glick et al.
patent: 3773737 (1973-11-01), Goodman et al.
patent: 3778476 (1973-12-01), Rembaum et al.
patent: 3839297 (1974-10-01), Wasserman et al.
patent: 3883901 (1975-05-01), Coquard et al.

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