Surgical aids containing pharmaceutically acceptable fixed-dried

Details Surgical aids containing pharmaceutically acceptable fixed-dried Surgical aids containing pharmaceutically acceptable fixed-dried

1996-12-31

1999-05-11

Sayala, Chhaya D.

Drug, bio-affecting and body treating compositions

Extract, body fluid, or cellular material of undetermined...

Blood

424 9372, 435 2, 435372, 436501, 530402, 604403, 606228, 602 41, A61K35/14;35/18

Patent

active

059026081

ABSTRACT:
Fixed-dried human blood platelets and processes for preparing them are disclosed. The platelets, upon reconstitution: adhere to thrombogenic surfaces; do not adhere to non-thrombogenic surfaces; undergo shape change (spreading) upon adhering to a thrombogenic surface; adhere to one another to form a hemostatic plug upon adhering to a thrombogenic surface; and release their granular contents. Surgical aids containing such platelets are also disclosed. The platelets are preferably fixed by a fixative such as formaldehyde, paraformaldehyde, or glutaraldehyde, or fixed by a permanganate fixate. The platelets are preferably dried by lyophilization.

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