Surgical adhesive material

Details Surgical adhesive material Surgical adhesive material

1992-03-23

1994-03-01

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

424530, 424423, 514801, 514 21, 514561, A61K 3516, A61K 37547

Patent

active

052905527

ABSTRACT:
The present invention provides a surgical adhesive comprising, in an aqueous composition, fibrinogen, FXIII, collagen, thrombin, Ca.sup.2+ and optionally, an antifibrinolytic agent. The present adhesive may be formed from the patient's plasma without the use of any added reagents for concentration or isolation of the fibrinogen. Conveniently, the adhesive is formulated as a two-part composition which is mixed together just prior to use.

REFERENCES:
patent: 3949073 (1976-04-01), Daniels et al.
patent: 4061731 (1977-12-01), Gottlieb
patent: 4627879 (1986-12-01), Rose et al.

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