Surfactant protein C esters

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C514S002600

Reexamination Certificate

active

11287197

ABSTRACT:
Novel surfactant protein C esters suitable for preparing pharmaceutical compositions for the treatment of infant respiratory distress syndrome and adult respiratory distress syndrome are described.

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Johansson, J., “Structure and properties of surfactant protein C”,Biochimica et Biophysica Acta, vol. 1408, pp. 161-172, (1998).
Nagasawa, H.T., “Augmentation of Human and Rat Lenticular Glutathione in Vitro by Prodrugs of γ-L-Glutamyl-L-cysteine”,J. Med. Chem., vol. 39, pp. 1676-1681, (1996).
Possmayer, F., “Pulmonary Perspective: A Proposed Nomenclature for Pulmonary Surfactant-associated Proteins1-3”,Am. Rev. Respir. Dis., vol. 138, pp. 990-998, (1988).
“Effects of rSP-C Surfactant on Oxygenation and Histology in a Rat-Lung-Lavage (RLL) Model of Acute Lung Injury”,Am. J. Respir. Crit. Care Med., vol. 158, pp. 270-278, 1998.

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