Surfactant compounds and uses thereof

Details Surfactant compounds and uses thereof Surfactant compounds and uses thereof

2007-03-27

2007-03-27

Richter, Johann R. (Department: 1616)

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

C562S586000

Reexamination Certificate

active

10485595

ABSTRACT:
A pharmaceutical aerosol formulation that includes a particulate medicament, one or more fluorocarbon or hydrogen-containing fluorocarbon propellants and a compound of the general formula (I)or a salt or solvate thereof is disclosed, whereinA represents a straight chain C1-16alkylene substituted by n groups of formula B;n represents an integer 1 to 3; andB independently represents C1-4fluoroalkylC0-6alkylene-, C1-4fluoroalkylC0-6alkylene-O—, or C1-4alkylC0-6alkylene-O—wherein at least one substituent of formula B contains at least one fluorine atom and each C1-4fluoroalkyl- moiety contains one or more fluorine atoms but not more than 3 consecutive perfluorinated carbon atoms. Compounds of formula (I) and uses of such compounds are also disclosed.

REFERENCES:
patent: 3250808 (1966-05-01), Moore, Jr. et al.
patent: 3498923 (1970-03-01), Bernett et al.
patent: 5849265 (1998-12-01), Li-Bovet et al.
patent: 2001/0046474 (2001-11-01), Weers et al.
patent: 0 021 739 (1981-01-01), None
patent: 02 49975 (1987-12-01), None
patent: 04 283538 (1992-10-01), None
patent: 053 31582 (1993-12-01), None
patent: 91/11173 (1991-08-01), None
patent: 91 14422 (1991-10-01), None
patent: 91/14422 (1991-10-01), None
patent: 92 00107 (1992-01-01), None
patent: 97/26017 (1997-07-01), None
patent: 97/30969 (1997-08-01), None
patent: 99/02193 (1999-01-01), None
patent: 99/03509 (1999-01-01), None
Dickinson, P. A. et al. “An Investigation of the Solubility of Various Compounds in the Hydrofluoroalkane Propellants and Possible Model Liquid Propellants,” J. Aerosol. Sci. 2000, 13(3), 179-186.
Lacy, C.; Armstrong, L. L.; Lipsy, R. J.; Lance, L. L. Drug Information Handbook, Lexi-Comp, Inc.: Cleveland, 1993, pp. 397.
Weinmayr, V.: “Hydrogen fluoride as a condensing agent. VI Reactions of fluoroolefins with formaldehyde in hydrogen fluoride,” J. Org. Chem., vol. 28, 1963, pp. 492-494, XP001183282.
Muller, N.: “Problematic chemical shifts of a fluorine-labeled surfactant and oil in some microemulsions systems,” J. Phys. Chem., vol. 86, 1982, pp. 2047-2049, XP002297139.
Muller, N., et. al., “Investigation of micelle structure by fluorine magnetic resonace. I. Sodium 10,10,10-trifluorocaprate and related compounds,” J. Phys. Chem., vol. 71, No. 4, Mar. 1967, pp. 957-962 XP002230279.
Gavlin, G., et al.: “The synthesis of omega-trifluorostearic acid and omega-trifluoro-n-octadecyl amine,” J. Org. Chem., vol. 21, Dec. 1956, pp. 1342-1347, XP002230280.
Park, J.D., et al., “Applicability of the Arndt-Eistert reaction to fluorinated acids and their derivatives,” J. Org. Chem., vol. 23, Aug. 1958, pp. 1166-1169 XP002230281.
Brace, N.O.: “Long chain alkanoic and alkenoic acids with perfluoroalkyl termial segments,” J. Org. Chem., vol. 27, Dec. 1962, pp. 4491-4498 XP001122366.
Gu, C., et al., “Dissociative and reactive hyperthermal ion-surface collisions . . . ” J. Am. Chem. Soc. vol. 121, 1999, pp. 10554-10562, XP001135063.
Graupe, M. , et. al., “Terminally perfluorinated long-chain alkanethiols” J. Fluorine Chem., vol. 93, No. 2, Feb. 4, 1999 pp. 107-115, XP004156221.

Affiliated with

Also associated with

Rating

Surfactant compounds and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Surfactant compounds and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Surfactant compounds and uses thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3737047