Coating processes – With post-treatment of coating or coating material – Solvent vapor treatment of coating
Patent
1999-01-08
2000-09-19
Dudash, Diana
Coating processes
With post-treatment of coating or coating material
Solvent vapor treatment of coating
427 21, 427 224, 427 23, B05D 300, B05D 304
Patent
active
061208477
ABSTRACT:
A method is provided for eliminating surface imperfections on a medical device having a drug release coating including a therapeutic substance in a polymeric carrier disposed on at least a portion of the medical device. The medical device is preferably a stent including wire-like members interconnected to form struts with open interstices therebetween. A therapeutic substance incorporate into a polymeric carrier is disposed on the surface of the stent through which process imperfections including polymeric fibers, polymeric particles or other polymeric surface aberrations or imperfections are formed. This imperfections are eliminated by contacting the polymeric coating with a vaporized solvent for a specified period of time.
REFERENCES:
patent: 2282274 (1942-05-01), Weiswasser et al.
patent: 3525634 (1970-08-01), Elkind et al.
patent: 3527650 (1970-09-01), Block
patent: 3676171 (1972-07-01), Spiller et al.
patent: 3684553 (1972-08-01), Van Dyk
patent: 3737499 (1973-06-01), Kamena
patent: 4027676 (1977-06-01), Mattei
patent: 4302418 (1981-11-01), Cullis et al.
patent: 4391797 (1983-07-01), Folkman et al.
patent: 4459317 (1984-07-01), Lambert
patent: 4487808 (1984-12-01), Lambert
patent: 4525409 (1985-06-01), Elesh
patent: 4768507 (1988-09-01), Fischell et al.
patent: 4770664 (1988-09-01), Gogolewski
patent: 4923464 (1990-05-01), DiPisa, Jr.
patent: 4969890 (1990-11-01), Sugita et al.
patent: 4994071 (1991-02-01), MacGregor
patent: 5019096 (1991-05-01), Fox, Jr. et al.
patent: 5092885 (1992-03-01), Yamada et al.
patent: 5102417 (1992-04-01), Palmaz
patent: 5222971 (1993-06-01), Willard et al.
patent: 5282823 (1994-02-01), Schwartz et al.
patent: 5304121 (1994-04-01), Sahatjian
patent: 5380299 (1995-01-01), Fearnot et al.
patent: 5383928 (1995-01-01), Scott et al.
patent: 5419760 (1995-05-01), Narciso, Jr.
patent: 5423885 (1995-06-01), Williams
patent: 5443458 (1995-08-01), Eury
patent: 5443496 (1995-08-01), Schwartz et al.
patent: 5447724 (1995-09-01), Helmus et al.
patent: 5449372 (1995-09-01), Schmaltz et al.
patent: 5449382 (1995-09-01), Dayton
patent: 5464650 (1995-11-01), Berg et al.
patent: 5512055 (1996-04-01), Domb et al.
patent: 5514154 (1996-05-01), Lau et al.
patent: 5527337 (1996-06-01), Stack et al.
patent: 5545208 (1996-08-01), Wolff et al.
patent: 5562922 (1996-10-01), Lambert
patent: 5569463 (1996-10-01), Helmus et al.
patent: 5569469 (1996-10-01), Lovrecich
patent: 5578075 (1996-11-01), Dayton
patent: 5591227 (1997-01-01), Dinh et al.
patent: 5605696 (1997-02-01), Eury et al.
patent: 5609629 (1997-03-01), Fearnot et al.
patent: 5616608 (1997-04-01), Kinsella et al.
patent: 5624411 (1997-04-01), Tuch
patent: 5626862 (1997-05-01), Brem et al.
patent: 5637113 (1997-06-01), Tartaglia et al.
patent: 5651986 (1997-07-01), Brem et al.
patent: 5660873 (1997-08-01), Nickolaychik et al.
patent: 5674241 (1997-10-01), Bley et al.
patent: 5674242 (1997-10-01), Phan et al.
patent: 5679400 (1997-10-01), Tuch
patent: 5697967 (1997-12-01), Dinh et al.
patent: 5700286 (1997-12-01), Tartaglia et al.
patent: 5716981 (1998-02-01), Hunter et al.
patent: 5733925 (1998-03-01), Kunz et al.
patent: 5755769 (1998-05-01), Richard et al.
patent: 5776184 (1998-07-01), Tuch
patent: 5779732 (1998-07-01), Amundson
patent: 5837008 (1998-11-01), Berg et al.
Bartoli et al., "In Vitro and In Vivo Antitumoral Activity of Free, and Encapsulated Taxol", J. Microencapsulation, vol. 7, No. 2, 1990, pp. 191-197.
Cox, David A., M.D. et al., "Effect of Local Delivery of Heparin and Methotrexate on Neointimal Proliferation in Stented Porcine Coronary Arteries", Coronary Artery Disease, vol. 3, No. 3, Mar. 1992, pp. 237-248.
Cox, D. A. et al., "Local Delivery of Heparin and Methotrexate Fails to Inhibit In Vivo Smooth Muscle Cell Proliferation", Supplement to Circulation Abstracts From the 64.sup.th Scientific Sessions, vol. 84, No. 4, Abstract No. 0284, 1991, p. II-71.
Dev, V. et al. "Kinetics of Drug Delivery to the Arterial Wall Via Polyurethane Coated Removable Nitinol Stent-Comparative Study of 2 Drugs", Circulation Abstracts From the 66.sup.th Scientific Sessions, vol. 88, No. 4, part 2, Abstract No. 1657, 1993, p. I-3.
Jampel, Henry D., M.D. et al., "In vitro Release of Hydrophobic Drugs From Polyanhydride Disks", Ophthalmic Surgery, dated prior to Jan. 8, 1991.
Lambert, T. et al., "A New Method For Arterial Drug Delivery Via Removable Stent", JACC, vol. 21, No. 2, Abstract No. 834-2, 1993, p. 483 A.
Lambert, T. et al., "Localized Arterial Drug Delivery From a Polymer Coated Removable Metallic Stent: Kinetics and Bioactivity of Forskolin", Circulation Abstracts From the 66.sup.th Scientific Sessions, vol. 88, No. 4, part 2, Abstract No. 1659, 1993, p. I-3.
Moses, Marsha A. et al., Inhibitors of Angiogenesis, Review, The Children's Hospital Medical Center, Boston, MA, dated prior to Jan. 8, 1999.
Pitt, C.G. et al., "The Design of Controlled Drug Delivery Systems Based on Biodegredable Polymers", Progress in Contraceptive Delivery Systems, M T P Press, Lancaster, 1980, pp. 17-18.
Tang, Chris et al., "Regression of Collagen-Induced Arthritis with Taxol, A Microtubule Stabilizer", Arthritis Rheum., vol. 36, No. 9 (Suppl.) 1993, p. 42.
"A Powerful Case for LOPID", Parke-Davis, dated prior to Jan. 8, 1999.
Whitborne, Richard, Ph.D., Presentation at the 2.sup.nd International Coronary Stenting Summit (Mar. 1-2, 1991).
Jacob Carmen
Wang Lixiao
Yang Dachuan
Dudash Diana
Sci-Med Life Systems, Inc.
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