Surface-treated sodium bicarbonate particle and molded preparati

Details Surface-treated sodium bicarbonate particle and molded preparati Surface-treated sodium bicarbonate particle and molded preparati

1989-12-15

1993-06-08

Lewis, Michael

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424490, 424470, 424469, 424717, 423422, A61K 946

Patent

active

052177190

ABSTRACT:
Surface-treated sodium bicarbonate particles, the surfaces of which are coated with sodium carbonate or its double salt, are disclosed. Heat treatment or irradiation with micro waves o infrared light converts the surfaces of sodium bicarbonate particles into sodium carbonate. The surface-treated sodium bicarbonate particles exhibit an increased capacity to bind with other sodium bicarbonate particles as well as with other components when they are molded. They can be used as an excellent binder for molding various preparations. The products produced have a prolonged storage stability.

REFERENCES:
patent: 261228 (1882-07-01), Hemje et al.
patent: 287128 (1883-10-01), Hemje
patent: 3701737 (1972-10-01), Goldstein
patent: 3852427 (1974-12-01), Hoffman et al.
patent: 3855398 (1974-12-01), Hoffmann et al.
patent: 4309408 (1982-01-01), Pathak et al.
Shreve, Norris R., Chemical Process Industries, 3rd Ed, 1967, pp. 228-231.

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