Surface plasmon resonance sensor chip

Details Surface plasmon resonance sensor chip Surface plasmon resonance sensor chip

2009-02-04

2011-10-11

Stafira, Michael P (Department: 2886)

Optics: measuring and testing

Sample, specimen, or standard holder or support

Reexamination Certificate

active

08035810

ABSTRACT:
A surface plasmon resonance sensor chip includes: a first dielectric layer; a metal layer disposed on the first dielectric layer; and a second dielectric layer covering the metal layer, the chip being provided with an opening that makes a part of a surface on the side of the second dielectric layer of the metal layer be exposed, and allows a measurement sample and the surface on the side of the second dielectric layer to contact each other, wherein an organic molecule film is provided at least one of between the first dielectric layer and the metal layer, and between the metal layer and the second dielectric layer.

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K. Kuhira et al., “Theoretical understanding of an absorption-based surface plasmon resonance sensor based on Kretchmann's theory.”, Anal. Chem. 74(3):696-701 (2002).
Shumaker-Parry J.S. et al., “Microspotting streptavidin and double-stranded DNA arrays on gold for high-throughput studies of protein-DNA interactions by surface plasmon resonance microscopy”, Anal. Chem., 76(4):918-929 (2004).

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