Surface plasmon resonance based nanoliter tear osmometer

Surgery – Diagnostic testing – Measuring or detecting nonradioactive constituent of body...

Reexamination Certificate

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C600S318000

Reexamination Certificate

active

07395103

ABSTRACT:
A medical diagnostic method utilizes a surface plasmon resonance apparatus provided with a sensing surface. A tear sample from an eye of a patient is placed into contact with the sensing surface. The surface plasmon resonance apparatus is then operated to determine osmolarity of the tear sample.

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Ho, H.P., et al., “Application of differential phase measurement technique to surface plasmon resonance sensors,” Sensors and Actuators B, vol. 96, pp. 554-559, 2003.

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