Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1994-12-28
1996-02-27
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
424487, 424495, 424499, A61K 916, A61K 950
Patent
active
054946832
ABSTRACT:
Dispersible particles consisting essentially of a crystalline anticancer agent having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 1000 nm. Anticancer compositions comprising the particles exhibit reduced toxicity and/or enhanced efficacy, and can be administered by IV bolus injection.
REFERENCES:
patent: 2671750 (1954-03-01), Macek
patent: 3881020 (1975-04-01), Nakamura et al.
patent: 4107288 (1978-08-01), Oppenheim
patent: 4225581 (1980-09-01), Kreuter et al.
patent: 4269821 (1981-05-01), Kreuter et al.
patent: 4540602 (1985-09-01), Motoyama
patent: 4826689 (1989-05-01), Violanto
patent: 4851421 (1989-07-01), Iwasaki et al.
patent: 5049322 (1991-09-01), Devissnguet
patent: 5091188 (1992-02-01), Haynes
patent: 5118525 (1992-06-01), Fessi
patent: 5124338 (1992-06-01), King
patent: 5132327 (1992-07-01), Patterson
patent: 5133908 (1992-07-01), Stainmesse et al.
patent: 5298262 (1994-03-01), Na et al.
patent: 5302401 (1994-04-01), Liversidge et al.
Lachman et al, "The Theory and Practice of Industrial Pharmacy" Chapter 2 (1986).
Remington's Pharmaceutical Sciences, 17th Edition, Chapter 20, Schott, H., "Colloidat Dispersions".
Goodman and Gilman, "the Pharmacological Basis of Therapeutics" 8th Edition, pp. 68-69.
Liversidge Elaine
Liversidge Gary G.
Sarpotdar Pramod P.
Benston, Jr. William E.
Eastman Kodak Company
Page Thurman K.
Rosenstein Arthur H.
LandOfFree
Surface modified anticancer nanoparticles does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Surface modified anticancer nanoparticles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Surface modified anticancer nanoparticles will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1677156