Surface modified anticancer nanoparticles

Details Surface modified anticancer nanoparticles Surface modified anticancer nanoparticles

1992-07-01

1995-03-21

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424489, A61K 914

Patent

active

053993632

ABSTRACT:
Dispersible particles consisting essentially of a crystalline anticancer agent having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 1000 nm. Anticancer compositions comprising the particles exhibit reduced toxicity and/or enhanced efficacy, and can be administered by IV bolus injection.

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Goodman and Gilman, "The Pharmacological Basis of Therapeutics", Eighth Edition, pp. 68-69.

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