Surface for the immobilization of ligands

Coating processes – Medical or dental purpose product; parts; subcombinations;... – Analysis – diagnosis – measuring – or testing product

Reexamination Certificate

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Details

C436S518000, C435S287100, C427S002110

Reexamination Certificate

active

07955638

ABSTRACT:
The present invention relates to binding surfaces for the immobilization of ligands, ligand surfaces and structured surface arrays which present a plurality of identical or different ligands. The invention further relates to a process for the production and the use of such surfaces and to specific binder molecules which can be used for the preparation thereof.

REFERENCES:
patent: 5834224 (1998-11-01), Ruger et al.
patent: 6475808 (2002-11-01), Wagner et al.
patent: 2002/0127577 (2002-09-01), Eichler et al.
patent: 0485874 (1992-05-01), None
patent: 0574000 (1993-12-01), None
patent: WO90/05503 (1990-05-01), None
Himmel et al., Fabrication of a carboxyl-terminated organic surface with self-assembly of functionalized terphenylthiols: the importance of hydrogen bond formation, 1998, J Am Chem Soc, 120: pp. 12069-12074.
Smith et al., Formation, spectroscopic characterization, and application of sulfhydryl terminated alkanethiol monolayers for the chemical attachment of DNA onto gold surfaces, 2001, Langmuir 17: pp. 2502-2507.
Derda, et al., Solid-phase synthesis of alkanethiols for the preparation of self-assembled monolayers, 2007, Langmuir, 23(22): 11164-11167.
“Molecular recognition at self-assembled monolayers: Optimization of surface functionalization”, J. Chem. Phys. 99 (9), Nov. 1, 1993 (4 pgs).

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